Linker immobilization of protein and oligonucleotide on indium-tin-oxide for detection of probe-target interactions by Kelvin physics.

نویسندگان

  • Marwan Saoud
  • Christophe Blaszykowski
  • Scott M Ballantyne
  • Michael Thompson
چکیده

This work describes a label-free microarray analysis technique capable of detecting biomolecule target interactions with probes being anchored with a new linker-diluent system on indium-tin-oxide. The method is based on the differential work function characteristics of the substrate measured by a scanning Kelvin nanoprobe in terms of contact potential difference signals.

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عنوان ژورنال:
  • The Analyst

دوره 134 5  شماره 

صفحات  -

تاریخ انتشار 2009